Principles of pharmacology : a tropical approach
This volume, first published in 1991, provides a useful and informative introduction to basic pharmacological principles and practice in the context of tropical medicine and diseases. The author discusses the cultural and environmental factors that affect the use of drugs in the tropics. The book highlights the potential inconsistencies and incompatibilities arising from the use of traditional and orthodox medicine, which can account for the extensive misuse of modern drugs among populations where the two systems are practised. Whilst emphasis is primarily given to the treatment of a wide range of tropical diseases, such as malaria, bilharzia and sickle-cell disease, the underlying principles are also fully explained to provide a conceptual framework for the academic exploration of cultural, genetic, environmental and nutritional factors affecting drug use in the tropics. The author also gives a concise treatment of systematic pharmacology. This makes the volume a useful text for students and practitioners of medicine and pharmacologists and specialists in tropical medicine, and for graduates studying chemotherapy of parasitic diseases. It will also be an important source of reference for medical and pharmacy students
Print Book, English, 1991
Cambridge University Press, Cambridge [England], 1991
xvi, 574 pages : illustrations ; 24 cm
9780521340953, 0521340950
19776881
Preface; Part I. General Background to Drug Usage in the Tropics: 1. Traditional medicine; 2. The problems of availability and quality of modern drugs in the tropics; Part II. Fundamental Pharmacodynamic Principles: 3. Measurement of drug response; 4. Receptors and drug response; Part III. Fundamental Principles in Drug Disposition: 5. Drug administration and factors affecting drug metabolism; 6. Pharmacokinetic principles; Part IV. Factors Affecting Drug Metabolism: 7. The influence of malnutrition and food-derived intoxicants; 8. Genetic factors affecting drug action; Part V. Selective Toxicity: 9. Antimicrobial drugs; 10. Antiprotozoal drugs; 11. Anthelmintics; 12. Anticancer and antiviral drugs; 13. Drug resistance; 14. Strategies for the development of new drugs; Part VI. Systematic Pharmacology: 15. Drug targets in the nervous system; 16. Noradrenergic mechanisms; 17. Cholinergic mechanisms; 18. Anaesthesia; 19. Pain and inflammation; 20. Drugs acting on the central nervous system; 21. Cardiovascular and renal systems; 22. Haemopoietic system; 23. Endocrine system; 24. Local hormones (autocoids); Index