Technical report on Salk poliomyelitis vaccine

Addendum Table amended animal antibody antitoxin application April 12 April 26 biologic products Biologics Control concentration Cutter Laboratories Cutter vaccine dating period dilution disease dose establishment experience field trial final container final vaccine formaldehyde immune inactivation process injection inoculation Institutes of Health intracerebral label Laboratory of Biologics licensed product Lilly live virus lots of vaccine lots tested merthiolate mice Minimum Requirements monkey test Monkey Tissue Culture myelitis National Foundation National Institutes negative tissue culture neutralization test NFIP nonparalytic Parke Davis particulates PHS REGULATIONS polio poliomyelitis vaccine poliomyelitis virus polyvalent lots Positive lots positive test potency tests prior procedures product license protocols Public Health Service recommended reference serums reinactivation release reported Salk vaccine samples serum Single strain lots single strain pool standards submitted Surgeon suspension tion tissue culture test titer trivalent organic arsenical trivalent pool vaccine produced viral virus pool Wyeth