Principles of Pharmacology: A Tropical ApproachThis volume, first published in 1991, provides a useful and informative introduction to basic pharmacological principles and practice in the context of tropical medicine and diseases. The author discusses the cultural and environmental factors that affect the use of drugs in the tropics. |
Contents
Measurement of drug response | 3 |
Receptors and drug response | 80 |
General Background to Drug Usage in the Tropics | 89 |
Drug administration and factors affecting drug metabolism | 111 |
The influence of malnutrition and foodderived intoxicants | 157 |
3 | 159 |
Antimicrobial drugs | 195 |
Antiprotozoal drugs | 225 |
80 | 262 |
Anticancer and antiviral drugs | 271 |
Drug resistance | 296 |
Drug targets in the nervous system | 337 |
Noradrenergic mechanisms | 351 |
Further reading | 463 |
Haemopoietic system | 502 |
Local hormones autocoids | 543 |
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Common terms and phrases
absorption acetylators acetylcholine activity administration adrenaline adrenoceptors affinity aflatoxin agonist aminoacids anaemia anaesthetics analgesic antagonists anti-inflammatory antibiotics aspirin atropine bacteria beta-adrenoceptors binding block blockers blood pressure cancer cardiac catecholamines cause cell membrane CHâ‚‚ CH2 CH2 chloroquine clinical compartment compounds COOH decrease deficiency depolarisation depression disease diuretics dopamine dose drug enzyme erythrocytes example excretion falciparum folic acid GABA glucose glycosides haemoglobin Hb-S heart histamine hormone hypertension increase infections inhibition inhibitors insulin isoprenaline kwashiorkor levodopa liver malaria mammalian mechanism of action metabolism metabolite molecule morphine neurones noradrenaline normal oral organisms parasite patients penicillin peptidoglycan peripheral pharmacokinetic pharmacological plasma plasma concentration potential prevent primaquine produce protein protein synthesis pyrimethamine quinidine red cells reduced release reserpine resistance response selective toxicity sickle cell side effects skeletal muscle sodium stimulation sulphonamides sympathetic nerves therapeutic therapy tion tissues treatment tropics tubocurarine tumour uptake vitamin worms