Principles of Pharmacology: A Tropical Approach

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Cambridge University Press, Feb 22, 1991 - Medical - 574 pages
This is a practical and informative introduction to basic pharmacological principles and practice, in general and in the context of tropical medicine and diseases. The author presents a concise treatment of systematic pharmacology, discussing the cultural and environmental factors that affect the use of drugs in the tropics. The book highlights the potential inconsistencies and incompatibilities that arise from the use of traditional and orthodox medicine, which can account for the extensive misuse of modern drugs among populations where the two systems are practiced. While emphasis is primarily given to the treatment of a wide range of tropical diseases including malaria, bilharzia and sickle-cell disease, the underlying principles are also fully explained; these provide a conceptual framework for the academic exploration of cultural, genetic, environmental and nutritional factors affecting drug use in the tropics. This will be a useful text for pharmacologists, specialists in tropical medicine and chemotherapy, as well as students and practioners in tropical environments.
 

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Contents

Traditional medicine
3
Measurement of drug response
51
Receptors and drug response
80
Drug administration and factors affecting drug metabolism
111
The influence of malnutrition and foodderived intoxicants
157
Antimicrobial drugs
195
Antiprotozoal drugs
225
Anthelmintics
251
Drug resistance
296
Drug targets in the nervous system
337
Noradrenergic mechanisms
351
Cardiovascular and renal systems
467
Haemopoietic system
502
Local hormones autocoids
543
Index
565
Copyright

Anticancer and antiviral drugs
271

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